We are responsible to ourselves for our own existence; consequently we want to be the true helmsman of this existence and refuse to allow our existence to resemble a mindless act of chance.
There are people who wish to make human life harder for no other reason than to be able afterwards to offer men their life-alleviating recipes their Christianity, for example.
The trodden worm turns itself. That is sagacious. It thereby lessens the probability of being again trodden on. In the language of morality: submissiveness.